It demonstrated significant impacts of changes in the foreign exchange rate. Cohen and Moon  used a MIPS model to analyze impacts of changes in a firm’s cost environment. It was found that scale economies, scope economies, and transportation costs could alter optimal facility network design strategies. Vidal and Stagecoaches  analyzed impacts of uncertainties on global supply chains through a MIPS model. Foreign exchange rate was identified to be influential on global supply chain configurations.
Using a two-stage optimization model, Giuliani et al.  evaluated trade-offs between risk pooling and logistics costs in a multi-plant network with commonality. Their analyses showed that impacts of operational cost parameters may be significant and non-intuitive. All these models suggested that cost parameters have significant impacts on manufacturing facility location decisions, and may even alter supply chain configuration strategies. However, they only considered a single objective of profits or costs.
The inconsideration of both costs and responsiveness was seen in the reconfiguration of global manufacturing and distribution network at Digital Equipment Corporation. It used a bi-objective model to minimize total costs and activity days. The model was implemented successfully with savings over $1 00 million . However, the application did not explore impacts of changes in cost parameters. Overall, there is a lack of using a bi-objective approach to analyze impacts of business environment changes on the configuration of Guns.